Aceglutamide (Aceglutamide Injection) 乙酰谷酰胺

Overview and indications

Aceglutamide is an important agent in the combination therapy of neurological disorders, providing support for and recovery of nervous system function.

It improves neuronal metabolism, enhances brain activity, and may help improve memory. It benefits nerve cells and their metabolism, supports nervous tension, lowers blood ammonia levels, and is able to cross the blood-brain barrier.

Aceglutamide (乙酰谷酰胺) is a solution for injection widely used in medicine, especially in the field of neurology. This acetylated derivative of glutamine possesses a range of therapeutic properties that make it an important component in the treatment of various neurological conditions.

Key properties of aceglutamide

Neuroprotective effect

• Aceglutamide improves the metabolism of nerve cells, supporting their function.
• It is able to cross the blood-brain barrier and participate in neurotransmission processes.
• It contributes to improved cognitive function and memory.

Lowering blood ammonia levels

• Important for patients with hepatic coma and other conditions associated with hyperammonemia.
• It promotes detoxification, reducing the toxic effect of ammonia on the body.

Use in the treatment of various diseases

• Effective in the treatment of traumatic brain injury, stroke, and other neurological disorders.
• Used for recovery after intense physical exertion, supporting nerve and muscle function.

Use of aceglutamide in cerebral palsy (CP)

Improving the metabolism of nerve cells

• Stimulates the recovery of nerve cell function by improving metabolism in neurons.
• Helps improve cognitive and motor function in children with cerebral palsy.

Reducing inflammatory processes

• Aceglutamide reduces levels of inflammatory cytokines such as TNF-α, IL-1, IL-6, and IL-8, decreasing inflammation in the brain.
• This improves the overall condition of the nervous system in children with cerebral palsy.

Support after neurosurgical interventions

• The drug aids the recovery of nerve function after brain surgery, supporting neuroplasticity.

Use of aceglutamide in other conditions

Cognitive impairment and memory decline

• Recommended for elderly people and post-stroke patients experiencing cognitive problems.
• Helps improve memory and cognitive function.

Recovery after physical exertion

• Aids recovery after intense training, supporting nerve and muscle function.

Mechanisms of action of aceglutamide

Detoxification

• After crossing the blood-brain barrier, it is broken down into glutamine and gamma-aminobutyric acid (GABA), promoting detoxification and improving the metabolism of nerve cells.

Support in stroke and motor disorders

• Stimulates cell growth and improves motor function, preventing the death of nerve cells.

Anti-ischemic activity

• Protects neurons from damage caused by ischemia, supporting their function under conditions of impaired blood circulation.

Recovery of nerve function

• Promotes the synthesis of acetylcholine, improving brain function and accelerating the recovery of brain tissue.

Reducing inflammatory processes

• Inhibits the excessive expression of inflammatory factors, reducing inflammatory reactions in brain injury.

Lowering ammonia levels

• Aceglutamide participates in ammonia metabolism, promoting its elimination from the body.

Administration and storage

• Administration: Intramuscular injection, intravenous drip
• Storage: In a dark, dry place at a temperature no higher than +20°C.